

Caffeine
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Caffeine is a central nervous system stimulant commonly found in coffee, tea, and various energy drinks. It is widely used in pharmaceuticals and personal care products for its stimulating effects.…
CAS Number
58-08-2
HS Code
29393000
INCI Name
Caffeine
Molecular Formula
C8H10N4O2
Caffeine is a central nervous system stimulant commonly found in coffee, tea, and various energy drinks. It is widely used in pharmaceuticals and personal care products for its stimulating effects. Caffeine enhances alertness and reduces fatigue, making it a popular ingredient in…
CAS Number
58-08-2
INCI Name
Caffeine
HS Code
29393000
Molecular Formula
C8H10N4O2
Get Pricing for This Product
Need pricing? Request a quote for this product and we'll get back to you shortly.
Speed Up Your Sample Testing Process
We deliver domestic samples within 24 - 48 hours, helping you evaluate product without delays.


| Property | Specification |
|---|---|
| Appearance | White crystalline powder |
| Odor | Odorless |
| Molecular Weight | 194.19 g/mol |
| Density / Specific Gravity | 1.23 g/cm³ |
| Ph (1% Aqueous Solution) | 6.9 |
| Assay / Purity | 98.5 - 101.0% (on an anhydrous basis) |
| Property | Specification |
|---|---|
| Pka | ~0.6 |
| Ionic Nature | Weakly basic |
| Incompatibilities | Strong oxidizing agents, strong acids, and strong bases. |
| Hazardous Reactions / Decomposition Products | Nitrogen oxides, carbon monoxide, irritating and toxic fumes and gases, carbon dioxide. |
| Property | Specification |
|---|---|
| Melting Point | 235-238 °C |
| Boiling Point | 178 °C at 760 mmHg (sublimes) |
| Flash Point | Not applicable |
| Decomposition Temperature | Decomposes before reaching its boiling point. |
| Thermal Stability | Stable for years under proper storage conditions. Heat above 178°C causes sublimation. |
| Application | Recommended / Max Dosage |
|---|---|
| Stimulant in Beverages | For most healthy adults, up to 400 milligrams (mg) per day is considered safe. This is equivalent to about four 8-ounce cups of brewed coffee. |
| Personal Care Products (Topical) - Under-eye creams and serums | 1-3% |
| Personal Care Products (Topical) - Body / cellulite creams | 1-5% |
| Personal Care Products (Topical) - Face products for puffiness | 1-2% |
| Personal Care Products (Topical) - Hair scalp serums | 0.5-1% |
| Dietary Supplements | Up to 400 mg per day is considered safe for most adults. |
| Food Additive (e.g., Carbonated Beverages) | The FDA has cited that less than 200 ppm (<0.02%) of caffeine is authorized for use in carbonated beverages. |
Caffeine anhydrous is the pure, dehydrated ('without water') crystalline powder form of caffeine - a white, odourless, bitter methylxanthine alkaloid (1,3,7-trimethylxanthine, CAS 58-08-2, C₈H₁₀N₄O₂). At ≥99% purity it lets formulators weigh an exact milligram dose, which is why anhydrous powder, not liquid or extract, is the standard caffeine source in supplements, energy drinks and pharmaceuticals. For the difference between the powder and everyday caffeine, see our guide on anhydrous caffeine vs caffeine.
Elchemy is a trusted caffeine powder supplier, manufacturer partner and distributor, supplying food-grade (FCC), USP/pharmaceutical and natural (green-coffee or tea-derived) caffeine to supplement, beverage, pharma and cosmetic manufacturers across 40+ countries. Every batch is third-party testable with a Certificate of Analysis, and samples ship within 24–48 hours.
As a B2B ingredient, Elchemy supplies caffeine to manufacturers and formulators for use in finished, correctly dosed products - not for direct-to-consumer sale of bulk pure powder.
Elchemy is a trusted caffeine powder supplier, manufacturer partner and distributor, serving supplement, sports-nutrition, beverage and pharmaceutical manufacturers across the USA, UK, UAE and 40+ countries. We supply synthetic and natural caffeine powder, each pre-audited for purity and consistency, with a Certificate of Analysis and third-party testing available on every batch.
Elchemy supplies bulk caffeine powder for manufacturing and commercial volumes - from trial kilograms to full-scale commercial volumes - in food, USP and natural grades. Whether you need pure caffeine powder for a pre-workout, a fat-burner or a functional beverage, share your grade and volume for a fast quote.
Wondering where to buy caffeine powder in bulk for your products? Elchemy ships anhydrous caffeine powder worldwide with US domestic stock for faster delivery. Submit the quote form with your grade, purity and volume and we'll confirm availability, price and lead time within 24–48 hours.
The caffeine powder price moves with grade (food, USP or natural), purity, order volume and origin, so Elchemy quotes live rather than publishing a fixed rate. Buyers benchmark the price per kg for trial lots and the per-drum or per-MT rate for contracts. Request a quote for an exact bulk caffeine powder price within 24–48 hours.
Commercial caffeine is produced either synthetically, from urea and related raw materials via the Traube purine synthesis, or naturally by extracting it from green coffee beans and tea leaves, often as a co-product of decaffeination.
Both routes are purified and dried to the same ≥99% anhydrous crystalline powder. The molecule is identical; the choice is about label positioning, natural versus synthetic, and cost.
Caffeine anhydrous powder ships in 25 kg fibre drums or kraft bags with food-grade inner liners, palletised for container loads and supplied to buyer requirements.
US domestic stock supports faster fulfilment; other origins typically transit 24–28 days to the US East Coast, on FOB, CIF or DDP terms. Store sealed in a cool, dry, ventilated area away from moisture and strong odours.
Caffeine is a potent stimulant, so accurate weighing and handling are essential - a very small mass carries a large dose. Handlers should wear gloves, goggles and a dust mask, avoid creating dust clouds, and work in a ventilated area. It is not a fire hazard under normal conditions.
This material is a B2B ingredient for professional formulation into correctly dosed finished products. A full GHS-aligned SDS ships with orders.
Manufactured synthetically via the Traube purine synthesis, from urea and dimethyl derivatives, or extracted naturally from green coffee beans and tea leaves during decaffeination, then purified and dried to ≥99% anhydrous powder.
In correctly dosed finished products caffeine is safe for most adults, but as a raw ingredient it is highly concentrated: excess intake can cause jitteriness, rapid heartbeat, insomnia and, at very high doses, serious toxicity. This is exactly why it is sold as a B2B ingredient for professional formulation, not for direct consumer use of bulk powder.
Caffeine anhydrous is the pure, dehydrated ('without water') crystalline powder form of caffeine - a white, odourless, bitter methylxanthine alkaloid (1,3,7-trimethylxanthine, CAS 58-08-2, C₈H₁₀N₄O₂). At ≥99% purity it lets formulators weigh an exact milligram dose, which is why anhydrous powder, not liquid or extract, is the standard caffeine source in supplements, energy drinks and pharmaceuticals. For the difference between the powder and everyday caffeine, see our guide on anhydrous caffeine vs caffeine.
Elchemy is a trusted caffeine powder supplier, manufacturer partner and distributor, supplying food-grade (FCC), USP/pharmaceutical and natural (green-coffee or tea-derived) caffeine to supplement, beverage, pharma and cosmetic manufacturers across 40+ countries. Every batch is third-party testable with a Certificate of Analysis, and samples ship within 24–48 hours.
As a B2B ingredient, Elchemy supplies caffeine to manufacturers and formulators for use in finished, correctly dosed products - not for direct-to-consumer sale of bulk pure powder.
Elchemy is a trusted caffeine powder supplier, manufacturer partner and distributor, serving supplement, sports-nutrition, beverage and pharmaceutical manufacturers across the USA, UK, UAE and 40+ countries. We supply synthetic and natural caffeine powder, each pre-audited for purity and consistency, with a Certificate of Analysis and third-party testing available on every batch.
Elchemy supplies bulk caffeine powder for manufacturing and commercial volumes - from trial kilograms to full-scale commercial volumes - in food, USP and natural grades. Whether you need pure caffeine powder for a pre-workout, a fat-burner or a functional beverage, share your grade and volume for a fast quote.
Wondering where to buy caffeine powder in bulk for your products? Elchemy ships anhydrous caffeine powder worldwide with US domestic stock for faster delivery. Submit the quote form with your grade, purity and volume and we'll confirm availability, price and lead time within 24–48 hours.
The caffeine powder price moves with grade (food, USP or natural), purity, order volume and origin, so Elchemy quotes live rather than publishing a fixed rate. Buyers benchmark the price per kg for trial lots and the per-drum or per-MT rate for contracts. Request a quote for an exact bulk caffeine powder price within 24–48 hours.
Commercial caffeine is produced either synthetically, from urea and related raw materials via the Traube purine synthesis, or naturally by extracting it from green coffee beans and tea leaves, often as a co-product of decaffeination.
Both routes are purified and dried to the same ≥99% anhydrous crystalline powder. The molecule is identical; the choice is about label positioning, natural versus synthetic, and cost.
Caffeine anhydrous powder ships in 25 kg fibre drums or kraft bags with food-grade inner liners, palletised for container loads and supplied to buyer requirements.
US domestic stock supports faster fulfilment; other origins typically transit 24–28 days to the US East Coast, on FOB, CIF or DDP terms. Store sealed in a cool, dry, ventilated area away from moisture and strong odours.
Caffeine is a potent stimulant, so accurate weighing and handling are essential - a very small mass carries a large dose. Handlers should wear gloves, goggles and a dust mask, avoid creating dust clouds, and work in a ventilated area. It is not a fire hazard under normal conditions.
This material is a B2B ingredient for professional formulation into correctly dosed finished products. A full GHS-aligned SDS ships with orders.
Manufactured synthetically via the Traube purine synthesis, from urea and dimethyl derivatives, or extracted naturally from green coffee beans and tea leaves during decaffeination, then purified and dried to ≥99% anhydrous powder.
In correctly dosed finished products caffeine is safe for most adults, but as a raw ingredient it is highly concentrated: excess intake can cause jitteriness, rapid heartbeat, insomnia and, at very high doses, serious toxicity. This is exactly why it is sold as a B2B ingredient for professional formulation, not for direct consumer use of bulk powder.
| Region | Max Allowed Level | Notes | Certification Body |
|---|---|---|---|
| United States | 0.02% | Caffeine is listed as Generally Recognized as Safe (GRAS) for use in cola-type beverages up to 0.02%. This GRAS status does not automatically extend to other food categories or dietary supplements. For dietary supplements, it is considered an "old" dietary ingredient and does not require a New Dietary Ingredient (NDI) notification. | FDA registration for food facilities. Subject to the Federal Food, Drug, and Cosmetic Act (FD&C Act). Products must comply with TSCA. |
| European Union | 3% | In cosmetics, caffeine functions as a skin conditioning and masking agent. It is listed in the CosIng database. | REACH registration is required for substances manufactured or imported in quantities of one tonne or more per year. GMP (Good Manufacturing Practices) for pharmaceuticals and cosmetics. |
| Canada | - | Caffeine is listed on the Natural Health Products Ingredients Database. For cosmetics, it must be listed on the label if present. | Site License and Product License for Natural Health Products. |
| India | - | Caffeine is regulated under the Food Safety and Standards Authority of India (FSSAI) for use in food products. | FSSAI license for food products. |
| Japan | - | Regulated under the Pharmaceutical and Medical Device Act (PMD Act) and the Act on Securing Quality, Efficacy and Safety of Products Including Pharmaceuticals and Medical Devices. | Must comply with standards set by the Ministry of Health, Labour and Welfare (MHLW). |
| Australia | - | Regulated by the Australian Industrial Chemicals Introduction Scheme (AICIS) and the Therapeutic Goods Administration (TGA) for therapeutic goods. | AICIS registration for industrial chemicals. |
| China | - | Caffeine is listed in the Inventory of Existing Cosmetic Ingredients in China (IECIC). | Registration or notification with the National Medical Products Administration (NMPA) for cosmetics. |
| Republic of Korea | - | Regulated by the Ministry of Food and Drug Safety (MFDS). | Must comply with MFDS regulations for food and cosmetics. |
| ASEAN | - | Regulated under the ASEAN Cosmetic Directive, which harmonizes cosmetic regulations among member states. | Product notification with the respective national regulatory authority. |
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