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Allantoin

Allantoin

ELACTAVIATM – ALTN

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A compound known for its soothing and skin conditioning properties, commonly used in skincare products.

CAS Number

97-59-6

HS Code

2933.21.0000

INCI Name

Allantoin

Molecular Formula

C₄H₆N₄O₃

Home/Products/Allantoin

Allantoin

ELACTAVIATM – ALTN

A compound known for its soothing and skin conditioning properties, commonly used in skincare products.

CAS Number

97-59-6

INCI Name

Allantoin

HS Code

2933.21.0000

Molecular Formula

C₄H₆N₄O₃

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Need pricing? Request a quote for this product and we'll get back to you shortly.

Speed Up Your Sample Testing Process

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Allantoin

Product Specification

AppearanceColorless to white solid
OdorOdorless
Molecular Weight (G/Mol)158.12
Density Or Specific Gravity0.951 g/mL at 25 °C (lit.)
Refractive Indexn20/D 1.442(lit.)
Ph (If Aqueous Solution)4.5 - 6 (5% in water, 20 °C)
Ph4.5 - 6 (5% in water, 20 °C)

Physical Properties

PropertySpecification
AppearanceColorless to white solid
OdorOdorless
Molecular Weight (G/Mol)158.12
Density Or Specific Gravity0.951 g/mL at 25 °C (lit.)
Refractive Indexn20/D 1.442(lit.)
Ph (If Aqueous Solution)4.5 - 6 (5% in water, 20 °C)
Ph4.5 - 6 (5% in water, 20 °C)

Chemical Properties

PropertySpecification
Pka8.96(at 25℃)

Thermal Properties

PropertySpecification
Melting Point239 °C
Flash Point230-234°C
Boiling PointDecomposes before boiling
Decomposition TemperatureDecomposes above melting point
Thermal StabilityStable at room temperature; decomposes at high temperatures

Processing Methods & Reference Formulations

A. Cosmetic cream

Dissolve allantoin in the water phase and heat to ensure complete solubility. Avoid adding during the cool-down phase, as it has limited solubility in cold water and may recrystallize.

Key IngredientsIndicative Dosage (% w/w)
Water (Aqua)70%
Glycerin5%
Cetearyl Alcohol4%
Caprylic/Capric Triglyceride6%
Isopropyl Myristate3%
Stearic Acid2%
Triethanolamine (TEA)0.8%
Benzalkonium Chloride (50% sol.)0.2%
Allantoin0.5%
Panthenol (Pro-Vitamin B5)1%
Tocopheryl Acetate (Vitamin E)0.5%
Dimethicone2%
Fragrance0.5%
Phenoxyethanol & Ethylhexylglycerin1%
Citric Acid (10% solution)0.4%

B. Hair shampoo

Add allantoin to the heated water phase to ensure proper dissolution, as it has low solubility in cold water. Mix well to avoid grittiness or sediment in the final shampoo.

Key IngredientsIndicative Dosage (% w/w)
Primary surfactants8-12%
Secondary surfactants2-5%
Butters20-40%
Allantoin0.1–1%
Water40-50%
Other UV Filters, Antioxidants, Humectants, Fragrance/flavor etc.

C. Facial Cleansers

When formulating facial cleansers, dissolve Allantoin (typically 0.1–0.5%) in the water phase by heating to ensure full solubility. Avoid overheating, as Allantoin can degrade at high temperatures. Stir gently to maintain clarity in clear formulations.

Key IngredientsIndicative Dosage (% w/w)
Deionized Water70%
EDTA-2Na0.10%
Sodium Cocoamphoacetate10%
Cocamidopropyl Betaine8%
Glycerine5%
Lauryl Glucoside4%
Panthenol1%
Allantoin0.3%

D. Sunscreen cream

When adding allantoin to sunscreen, dissolve it in the water phase at 0.05–0.5% concentration and heat gently to ensure full solubilization. Maintain final pH between 5.0–7.0 for stability and compatibility with UV filters. Stir thoroughly to ensure uniform dispersion.

Key IngredientsIndicative Dosage (% w/w)
Homosalate6-10%
Ethylhexyl Methoxycinnamate5-9%
Ethylhexyl Salicylate2-6%
4-Methylbenzylidene Camphor2-5%
Titanium Dioxide2-6%
Polydimethylsiloxane3-8%
Propylene Glycol3-6%
Allantoin0.05% to 0.3%
Plant extracts (e.g., safflower extract)0.3-0.6%
Emulsifiers and thickeners

Dosing Guidelines

A. Dosing by Application

ProductsAuthorized dosage %
Skin Care0.5-2%
Hair shampoo0.1-1%
Other Personal Care0.2-2%

About Allantoin

About Allantoin

Regulatory Compliance

RegionMax Allowed LevelNotesCertification Body
United States2%The US FDA list Allantoin as a over-the-counter (OTC) skin protectant at 0.5% to 2%.FDA
European Union-No explicit legal maximum, can be used at any safe concentrationSCCS (Scientific Committee on Consumer Safety)
India-No BIS-specific limit-
Japan-No specific limitMHLW – Ministry of Health, Labour and Welfare
Australia-No statutory maximum-
China-No statutory maximumNMPA - National Medical Products Administration
Korea, Republic of-No statutory maximumMFDS - Ministry of Food and Drug Safety
ASEAN-No statutory maximum-

FAQs - Allantoin

Can Allantoin be used in pharmaceuticals?
Yes, it is widely used in wound healing and skincare.
What is the shelf life of Allantoin?
2 years.
How is Allantoin packaged for export?
Typically in bags or drums.
Does Allantoin meet international safety standards?
Yes, it is approved globally.
Is Allantoin safe for sensitive skin?
Yes, it is known for its soothing properties.

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