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Triacetin, also known as glycerol triacetate, is a versatile chemical compound used in various industries. It serves as a plasticizer, solvent, and humectant, enhancing the flexibility, stability, and…
CAS Number
102-76-1
HS Code
29.15.39.90
INCI Name
Triacetin
Molecular Formula
C₉H₁₄O₆
Triacetin, also known as glycerol triacetate, is a versatile chemical compound used in various industries. It serves as a plasticizer, solvent, and humectant, enhancing the flexibility, stability, and moisture retention of products. Commonly used in food, pharmaceuticals, and…
CAS Number
102-76-1
INCI Name
Triacetin
HS Code
29.15.39.90
Molecular Formula
C₉H₁₄O₆
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| Property | Specification |
|---|---|
| Appearance | Colorless, oily liquid |
| Odor | Smellless |
| Molecular Weight | 218.21 |
| Density | 1.16 g/cm³ |
| Specific Gravity (20°C) | 1.154–1.164 g/ml |
| Specific Gravity (25°C) | 1.154–1.158 g/ml |
| Viscosity (20°C) | 23 mPa·s |
| Viscosity (25°C) | approx. 17 mPa.s |
| Refractive Index (20°C) | 1.430–1.435 |
| Refractive Index (25°C) | 1.429–1.431 |
| Ph (50 G/L Aqueous Solution, 20°C) | 5.0–6.0 |
| Assay / Purity | ≥99.5% |
| Property | Specification |
|---|---|
| Ionic Nature | Non-ionic |
| Incompatibilities | Strong oxidizing agents. |
| Hazardous Decomposition Products | When heated to decomposition it emits acrid smoke and irritating fumes. |
| Property | Specification |
|---|---|
| Melting Point | 3 °C |
| Boiling Point | 258 °C |
| Flash Point | 138 °C (closed cup) |
| Autoignition Temperature | 433 °C |
| Thermal Stability | Stable under recommended storage conditions. |
This formulation describes a typical aqueous-based film coating for pharmaceutical tablets, where triacetin acts as a hydrophilic plasticizer to improve the flexibility and durability of the polymer film.
| Key Ingredients | Indicative Dosage (% w/w) |
|---|---|
| Hydroxypropyl Methylcellulose (HPMC) | Base Polymer |
| Triacetin | 10–35% |
| Water | q.s. to desired solids content |
This formulation creates a stable microemulsion for flavor delivery, leveraging triacetin as the oil phase.
| Key Ingredients | Indicative Dosage (% w/w) |
|---|---|
| Triacetin (Oil Phase) | 25% |
| Polysorbate 20 (Surfactant) | 25% |
| Polyoxyl 35 Castor Oil (Cosurfactant) | 25% |
| Water | 50% |
| Application | Recommended / Max Dosage |
|---|---|
| Pharmaceutical Tablet & Capsule Coatings | 10–35% w/w of the polymer content |
| Flavoring Agent / Solvent | Governed by Good Manufacturing Practices (GMP) |
| Chewing Gum (as Plasticizer) | Governed by Good Manufacturing Practices (GMP) |
| Baked Goods (as Humectant) | Governed by Good Manufacturing Practices (GMP) |
| Beverages (Non-alcoholic) | Governed by Good Manufacturing Practices (GMP) |
| Confections and Frostings | Governed by Good Manufacturing Practices (GMP) |
| Hard Candy | Governed by Good Manufacturing Practices (GMP) |
| Frozen Dairy Desserts | Governed by Good Manufacturing Practices (GMP) |
Triacetin, also known as glycerol triacetate, is a highly versatile compound used across multiple industries. As a plasticizer, it enhances the flexibility and durability of polymers, making it a crucial component in the production of plastics and resins. In the pharmaceutical sector, Triacetin acts as a solvent, improving the solubility and bioavailability of active ingredients, which is essential for effective drug formulations. Its role as a humectant in personal care products helps retain moisture, enhancing skin hydration and product stability. Triacetin is also used as a flavoring agent in the food industry, ensuring uniform distribution and stability of flavors. Its compatibility with other film-forming agents makes it ideal for coatings and films, providing a glossy finish and protective barrier. Manufacturers and suppliers of Triacetin focus on producing high-purity grades to meet the stringent demands of these industries. The production process is carefully controlled to ensure consistency and stability, which are crucial for the compound’s effectiveness in various applications. Sustainability is an increasing focus for Triacetin manufacturers, with many adopting greener practices to minimize their environmental impact. These efforts include optimizing energy use during production and reducing waste emissions. The trend toward eco-friendly manufacturing aligns with the growing demand for sustainable raw materials in the chemical industry.
Triacetin, also known as glycerol triacetate, is a highly versatile compound used across multiple industries. As a plasticizer, it enhances the flexibility and durability of polymers, making it a crucial component in the production of plastics and resins. In the pharmaceutical sector, Triacetin acts as a solvent, improving the solubility and bioavailability of active ingredients, which is essential for effective drug formulations. Its role as a humectant in personal care products helps retain moisture, enhancing skin hydration and product stability. Triacetin is also used as a flavoring agent in the food industry, ensuring uniform distribution and stability of flavors. Its compatibility with other film-forming agents makes it ideal for coatings and films, providing a glossy finish and protective barrier. Manufacturers and suppliers of Triacetin focus on producing high-purity grades to meet the stringent demands of these industries. The production process is carefully controlled to ensure consistency and stability, which are crucial for the compound’s effectiveness in various applications. Sustainability is an increasing focus for Triacetin manufacturers, with many adopting greener practices to minimize their environmental impact. These efforts include optimizing energy use during production and reducing waste emissions. The trend toward eco-friendly manufacturing aligns with the growing demand for sustainable raw materials in the chemical industry.
| Region | Max Allowed Level | Notes | Certification Body |
|---|---|---|---|
| Australia | - | Approved as a food additive (A1518) for use as a humectant and solvent in flavorings. | FSANZ approval. |
| Canada | - | Listed in the List of Permitted Food Additives with Other Generally Accepted Uses to be used as a carrier or extraction solvent in food. Not listed on the Cosmetic Ingredient Hotlist. | Health Canada approval for food use. |
| China | - | Listed in the Inventory of Existing Cosmetic Ingredients in China (IECIC). | NMPA (for cosmetics). |
| India | - | Listed with HSN code 29153900. | - |
| United States | - | Affirmed as Generally Recognized as Safe (GRAS) for direct use in human food and animal feed. The Cosmetic Ingredient Review (CIR) Expert Panel concluded it is safe as used in cosmetic formulations. | FDA (for food/pharma use), TSCA Inventory listing. |
| European Union | - | Approved as a food additive (E1518) under Regulation (EC) No 1333/2008, for uses such as a carrier solvent in flavorings and in chewing gum. Not specifically restricted in cosmetics. | REACH registration. |
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