

ELACTAVIA – HYA
Hyaluronic Acid is a naturally occurring glycosaminoglycan found in connective tissues, skin, and eyes. It is renowned for its exceptional ability to retain moisture, making it a popular ingredient in skincare and cosmetic products. In medical applications, it is used in joint injections and eye surgeries due to its lubricating properties.
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CAS Number
9004-61-9
HS Code
3913.90.90
Molecular Formula
C₂₈H₄₄N₂O₂₃
INCI Name
Hyaluronic Acid
Hyaluronic Acid is a naturally occurring glycosaminoglycan found in connective tissues, skin, and eyes. It is renowned for its exceptional ability to retain moisture, making it a popular ingredient in skincare and cosmetic products. In medical applications, it is used in joint…
CAS Number
9004-61-9
INCI Name
Hyaluronic Acid
HS Code
3913.90.90
Molecular Formula
C₂₈H₄₄N₂O₂₃
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ELACTAVIA – HYA
| Property | Specification |
|---|---|
| Odor | Odorless |
| Appearance | White powder |
| Molecular Weight (G/Mol) | 403.31 |
| Ph (If Aqueous Solution) | 5.0-8.5 |
| Property | Specification |
|---|---|
| Pka | 3-4 |
| Water Solubility | 5 mg/mL |
| Incompatibilities | Strong oxidizers, strong acids/bases, heavy metal salts |
| Property | Specification |
|---|---|
| Boiling Point | 1274.4 ± 65.0°C |
| Melting Point | 241-247°C |
| Decomposition Temperature | Decomposes above 200 °C |
Add hyaluronic acid to the water phase at low temperatures to preserve its structure and hydration properties. Use a compatible thickener or stabilizer to maintain uniform dispersion and enhance skin feel without affecting emulsion stability.
| Key Ingredients | Indicative Dosage (% w/w) |
|---|---|
| Sunflower Oil | 25% |
| Beeswax | 15% |
| Candelilla Wax | 5% |
| Shea Butter | 10% |
| Coconut Oil | 15% |
| Jojoba Oil | 5% |
| Hyaluronic Acid (1%) | 1% |
| Vitamin E Acetate1 | 1% |
| Tocopherol | 0.5% |
| Deionized Water | 21% |
| Fragrance (optional) | 0.5% |
Add hyaluronic acid to the cool-down phase of shampoo production to prevent degradation and to ensure it is well-dispersed in the aqueous phase. Avoid high temperatures and harsh surfactants to maintain stability. Mix gently but thoroughly to ensure even distribution without foaming issues.
| Key Ingredients | Indicative Dosage (% w/w) |
|---|---|
| Primary Surfactants | 8-12% |
| Secondary Surfactants | 2-8% |
| Foaming Agents | 3-8% |
| Hyaluronic Acid | 0.1–0.5% |
| Water | 60-80% |
| pH adjusters, Fragrances, Preservatives, Conditioning Emollients etc. |
Use encapsulated or anhydrous forms of hyaluronic acid to maintain stability in the oil-based lip balm matrix. Ensure even dispersion and compatibility with waxes and oils to avoid grittiness or phase separation.
| Key Ingredients | Indicative Dosage (% w/w) |
|---|---|
| Oils/Emollients | 40-60% |
| Butters | 20-40% |
| Waxes | 15-25% |
| Hyaluronic Acid | 0.1–0.5% |
| Humectants, Antioxidants, Fragrance/Flavor, Other Actives etc. |
In makeup foundation formulation, dissolve Hyaluronic Acid in the aqueous phase, ideally hydrating it fully before emulsification to prevent clumping. Add it during the cool-down phase to preserve its moisturizing properties.
| Key Ingredients | Indicative Dosage (% w/w) |
|---|---|
| Water (Aqua) | 50% |
| Cyclopentasiloxane | 10% |
| Dimethicone | 5% |
| Glycerin | 3% |
| Hyaluronic Acid | 2% |
| Butylene Glycol | 2% |
| Sodium Chloride | 0.5% |
| Titanium Dioxide | 5% |
| Iron Oxides | 5% |
| Phenoxyethanol | 0.8% |
| Ethylhexylglycerin | 0.2% |
| Fragrance |
| Products | Authorized dosage % |
|---|---|
| Sunscreen Lotions, Creams | 0.1-2% |
| Cosmetics lip balms | 0.1-0.5% |
| Hair Product shampoos | 0.1-0.5% |
Hyaluronic Acid, a key ingredient in modern skincare and medical treatments, is celebrated for its remarkable moisture-retaining properties. As a naturally occurring substance in the human body, it plays a crucial role in maintaining skin hydration and joint lubrication. Hyaluronic Acid manufacturers focus on producing high-purity grades suitable for various applications, including cosmetics, pharmaceuticals, and food supplements. Its ability to hold up to 1,000 times its weight in water makes it an indispensable component in anti-aging and hydrating skincare formulations. In the medical field, Hyaluronic Acid is used in joint injections to alleviate pain and improve mobility in osteoarthritis patients. It is also a vital component in ophthalmic solutions, providing lubrication and moisture to the eyes. The production of Hyaluronic Acid involves advanced biotechnological processes to ensure consistency and efficacy. As the demand for natural and effective skincare ingredients grows, Hyaluronic Acid suppliers are committed to sustainable and ethical sourcing practices. This aligns with the increasing consumer preference for eco-friendly and cruelty-free products. Hyaluronic Acid's versatility extends to the food industry, where it is used as a dietary supplement to support joint and skin health. Its widespread use across multiple sectors underscores its importance as a fundamental compound in modern industry.
Streptococcus zooepidemicus ferments glucose and nutrients under aerobic conditions to biosynthesize hyaluronic acid (Yield ~70–90%)
Streptococcus zooepidemicus ferments glucose and nutrients under aerobic conditions to biosynthesize hyaluronic acid (Yield ~70–90%) Raw Materials: Glucose, Streptococcus fermentation or animal tissue Overall Formula: Glucose + Nutrients + Streptococcus spp. → Hyaluronic Acid + CO₂ + Organic Acids + Biomass
Hyaluronic Acid, a key ingredient in modern skincare and medical treatments, is celebrated for its remarkable moisture-retaining properties. As a naturally occurring substance in the human body, it plays a crucial role in maintaining skin hydration and joint lubrication. Hyaluronic Acid manufacturers focus on producing high-purity grades suitable for various applications, including cosmetics, pharmaceuticals, and food supplements. Its ability to hold up to 1,000 times its weight in water makes it an indispensable component in anti-aging and hydrating skincare formulations. In the medical field, Hyaluronic Acid is used in joint injections to alleviate pain and improve mobility in osteoarthritis patients. It is also a vital component in ophthalmic solutions, providing lubrication and moisture to the eyes. The production of Hyaluronic Acid involves advanced biotechnological processes to ensure consistency and efficacy. As the demand for natural and effective skincare ingredients grows, Hyaluronic Acid suppliers are committed to sustainable and ethical sourcing practices. This aligns with the increasing consumer preference for eco-friendly and cruelty-free products. Hyaluronic Acid's versatility extends to the food industry, where it is used as a dietary supplement to support joint and skin health. Its widespread use across multiple sectors underscores its importance as a fundamental compound in modern industry.
Streptococcus zooepidemicus ferments glucose and nutrients under aerobic conditions to biosynthesize hyaluronic acid (Yield ~70–90%)
Streptococcus zooepidemicus ferments glucose and nutrients under aerobic conditions to biosynthesize hyaluronic acid (Yield ~70–90%) Raw Materials: Glucose, Streptococcus fermentation or animal tissue Overall Formula: Glucose + Nutrients + Streptococcus spp. → Hyaluronic Acid + CO₂ + Organic Acids + Biomass
| Region | Max Allowed Level | Notes | Certification Body |
|---|---|---|---|
| United States | - | No explicit maximum concentration set by the FDA for hyaluronic acid (HA) in cosmetic product | FDA |
| European Union | - | No explicit maximum concentration | - |
| India | - | The BIS does not specify a maximum limit for HA in cosmetics. | - |
| Japan | - | Japanese regulations do not set a specific maximum concentration for HA in cosmetics. | MHLW – Ministry of Health, Labour and Welfare |
| Australia | - | No explicit max for finished products. | - |
| China | - | No statutory maximum | NMPA - National Medical Products Administration |
| Korea, Republic of | - | No statutory maximum | MFDS - Ministry of Food and Drug Safety |
| ASEAN | - | No statutory maximum | - |
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