Chlorhexidine Digluconate
ELPROTECTTM – CDH20
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Chlorhexidine Digluconate is a broad-spectrum antimicrobial agent widely used in healthcare and personal care products. It is effective against a variety of bacteria, fungi, and viruses, making it a…
CAS Number
18472-51-0
HS Code
2925.20.2000 / 2925.2990 / 3808.94.00
INCI Name
Chlorhexidine Digluconate
Molecular Formula
C₂₂H₃₀Cl₂N₁₀·2C₆H₁₂O₇
Chlorhexidine Digluconate
ELPROTECTTM – CDH20
Chlorhexidine Digluconate is a broad-spectrum antimicrobial agent widely used in healthcare and personal care products. It is effective against a variety of bacteria, fungi, and viruses, making it a popular choice for disinfectants, antiseptics, and oral care products. Its…
CAS Number
18472-51-0
INCI Name
Chlorhexidine Digluconate
HS Code
2925.20.2000 / 2925.2990 / 3808.94.00
Molecular Formula
C₂₂H₃₀Cl₂N₁₀·2C₆H₁₂O₇
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Product Specification
Physical Properties
| Property | Specification |
|---|---|
| Appearance | Clear Liquid |
| Molecular Weight (G/Mol) | 897.8 |
| Density Or Specific Gravity | 1.06 g/mL at 25 °C(lit.) |
| Viscosity | 2.51mm2/s |
Chemical Properties
| Property | Specification |
|---|---|
| Water Solubility | 750g/L at 20℃ |
Thermal Properties
| Property | Specification |
|---|---|
| Boiling Point | 97 °C / 206.6 °F |
Processing Methods & Reference Formulations
A. Antimicrobial Hand wash
Add CHG at <40°C during the final mixing stage to prevent thermal degradation. Mix gently and uniformly to avoid foam formation and ensure even distribution.
| Key Ingredients | Indicative Dosage (% w/w) |
|---|---|
| Chlorhexidine Gluconate (20% active solution) | 2% |
| Hydroxyethylcellulose | 0.8% |
| Propylene Glycol | 3% |
| Alkyl Polyglucoside | 6% |
| Cocamidopropyl PG-Dimonium Chloride Phosphate | 0.25% |
| Lauryl Dimethyl Amine Oxide | 0–2% |
| Polyoxyethylene-(10) Tridecanol Ethoxylate | 1–3% |
| Deionized Water | ~87% |
B. Skin Cleanser
Add CHG during the cool-down phase to avoid thermal degradation. Mix gently to avoid foaming and ensure uniform distribution. Maintain the formulation pH around 5.5–7.0. CHG is most stable and effective in this range; acidic pH may reduce efficacy and alkaline pH may degrade the molecule.
| Key Ingredients | Indicative Dosage (% w/w) |
|---|---|
| Chlorhexidine Gluconate | 2.0% |
| Nonionic Surfactant (e.g., fatty alcohol ethoxylate C12–C15, ~10 EO) | 5.0% |
| Polyoxyethylene-polyoxypropylene Copolymer (e.g., Pluronic) | ≤10.0% |
| Purified Water | Balance (~85%) |
C. Mouth Wash
CHG is most stable and effective in mildly acidic to neutral pH. Incorporate CHG during the cool-down phase to prevent decomposition. Mix gently and avoid prolonged exposure to heat or light.
| Key Ingredients | Indicative Dosage (% w/w) |
|---|---|
| Chlorhexidine Gluconate | 0.2% |
| Polyvinylpyrrolidone (PVP) | 15% |
| Sodium Saccharin | 0.1% |
| Sodium Acetate | 1.4% |
| Glycerin | 10% |
| Dye Solution | 0.1% |
| Ethanol | 5% |
| Cremophor RH-60 (Polyoxyl 60–Hydrogenated Castor Oil) | 0.2% |
| Flavor Oil | 0.12% |
| Deionized Water | ~73% |
Dosing Guidelines
A. Dosing by Application
| Products | Typical dosage % |
|---|---|
| Oral rinse (mouthwash, dental) | 0.12–0.2% |
| Skin antiseptic/preoperative scrub | 2-4% |
About Chlorhexidine Digluconate
Chlorhexidine Digluconate manufacturers and suppliers provide a versatile antimicrobial agent used extensively in healthcare and personal care industries. Known for its broad-spectrum efficacy, it is a key ingredient in disinfectants, antiseptics, and oral care products. Chlorhexidine Digluconate disrupts microbial cell membranes, ensuring high efficacy in preventing infections and maintaining hygiene. Manufacturers focus on producing high-purity grades to meet stringent industry standards, ensuring safety and effectiveness. The compound's versatility extends to veterinary applications, highlighting its importance across various sectors. As a leading choice for infection control, Chlorhexidine Digluconate continues to be a critical component in maintaining public health and safety.
- Broad-Spectrum Antimicrobial: Effective against bacteria, fungi, and viruses, making it ideal for healthcare and personal care applications.
- High Efficacy: Disrupts microbial cell membranes, ensuring rapid and effective microbial control.
- Versatile Applications: Used in healthcare, oral care, personal care, and veterinary products, demonstrating its wide-ranging utility.
- Safe and Reliable: Manufactured to high-purity standards, ensuring safety and effectiveness in various formulations.
- Preferred for Infection Control: A leading choice in disinfectants and antiseptics for its proven efficacy and safety profile.
About Chlorhexidine Digluconate
Chlorhexidine Digluconate manufacturers and suppliers provide a versatile antimicrobial agent used extensively in healthcare and personal care industries. Known for its broad-spectrum efficacy, it is a key ingredient in disinfectants, antiseptics, and oral care products. Chlorhexidine Digluconate disrupts microbial cell membranes, ensuring high efficacy in preventing infections and maintaining hygiene. Manufacturers focus on producing high-purity grades to meet stringent industry standards, ensuring safety and effectiveness. The compound's versatility extends to veterinary applications, highlighting its importance across various sectors. As a leading choice for infection control, Chlorhexidine Digluconate continues to be a critical component in maintaining public health and safety.
- Broad-Spectrum Antimicrobial: Effective against bacteria, fungi, and viruses, making it ideal for healthcare and personal care applications.
- High Efficacy: Disrupts microbial cell membranes, ensuring rapid and effective microbial control.
- Versatile Applications: Used in healthcare, oral care, personal care, and veterinary products, demonstrating its wide-ranging utility.
- Safe and Reliable: Manufactured to high-purity standards, ensuring safety and effectiveness in various formulations.
- Preferred for Infection Control: A leading choice in disinfectants and antiseptics for its proven efficacy and safety profile.
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