ELACTAVIA – SCA
Salicylic Acid
ELACTAVIATM – SCA
Salicylic acid is a beta-hydroxy acid derived from willow bark, distinguished by its oil-solubility, exfoliating, and anti-inflammatory properties, extensively utilized in acne treatments, exfoliants, and dermatological formulations due to its ability to penetrate sebum, clear pores, and regulate skin cell turnover.
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CAS Number
69-72-7
HS Code
2918.21.10
Molecular Formula
C₇H₆O₃
INCI Name
Salicylic Acid
Salicylic Acid
ELACTAVIATM – SCA
Salicylic acid is a beta-hydroxy acid derived from willow bark, distinguished by its oil-solubility, exfoliating, and anti-inflammatory properties, extensively utilized in acne treatments, exfoliants, and dermatological formulations due to its ability to penetrate sebum, clear…
CAS Number
69-72-7
INCI Name
Salicylic Acid
HS Code
2918.21.10
Molecular Formula
C₇H₆O₃
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ELACTAVIA – SCA
Product Specification
Physical Properties
| Property | Specification |
|---|---|
| Ph | 3.21(1 mM solution);2.57(10 mM solution);2.02(100 mM solution) |
| Odor | Faint phenolic |
| Density | 1.44 |
| Appearance | White to off-white solid |
| Refractive Index | 1.565 |
| Molecular Weight (G/Mol) | 138.12 |
| Ph (If Aqueous Solution) | 3.21(1 mM solution);2.57(10 mM solution);2.02(100 mM solution) |
| Density Or Specific Gravity | 1.44 |
Chemical Properties
| Property | Specification |
|---|---|
| Pka | 2.98(at 25℃) |
Thermal Properties
| Property | Specification |
|---|---|
| Flash Point | 157 °C |
| Boiling Point | 211 °C(lit.) |
| Melting Point | 158-161 °C(lit.) |
Processing Methods & Reference Formulations
A. Hair Anti-Dandruff Shampoo
When adding salicylic acid to hair shampoo, dissolve it in a co-solvent for better solubility. Add it during the cool-down phase to ensure stability and scalp compatibility.
| Key Ingredients | Indicative Dosage (% w/w) |
|---|---|
| Sulphur | 0.75% |
| Salicylic acid | 0.5–1.75% |
| Benzoic acid | 1.0–2.0 % |
| Sodium lauryl sulphate | 20% |
| Urea | 0.75% |
| Citric acid | 0.5% |
| Sodium EDTA | 0.5% |
| Guar gum | 1.5% |
| Tween 80 | 0.5% |
| Distilled water | 65-75% |
B. Cosmetic Ointment
When formulating with salicylic acid in cosmetic ointments, dissolve it in a suitable solvent before incorporation to ensure uniform distribution. Add the solution to the oil phase or during the cooling stage to prevent crystallization. Ensure the final pH is below 4 for optimal efficacy and stability.
| Key Ingredients | Indicative Dosage (% w/w) |
|---|---|
| 10–12% | |
| Salicylic acid | 0.5% |
| White vaseline | 62% |
| Stearic acid | 10% |
| Castor oil | 4% |
| Camphor | 1% |
| Sodium dodecyl benzene sulfonate | 0.9% |
| Ethylparaben | 0.1% |
| Water | 10% |
C. Skin Cleansers
When adding Salicylic Acid to skin cleansers, dissolve it in a small amount of ethanol or propylene glycol before incorporation to ensure proper solubility. Add the solution to the water phase and maintain the final pH between 3.5 and 4.5 for optimal effectiveness. Avoid high temperatures to prevent degradation during processing.
| Key Ingredients | Indicative Dosage (% w/w) |
|---|---|
| Water | 85.6% |
| Glycerine | 1% |
| Ethanol | 10% |
| Polyethylene Glycol | 1% |
| Salicylic acid | 0.5% |
| Benzoic acid | 0.1% |
| Sodium citrate | 0.35% |
| Vitamin E acetate | 0.1% |
| Fragrance, Colorants, others |
D. Moisturizing Cream
Add Salicylic Acid as a fine powder dispersed evenly in the aqueous phase before emulsification for uniform delivery. Ensure even dispersion and monitor for potential crystallization during cooling.
| Key Ingredients | Indicative Dosage (% w/w) |
|---|---|
| Water | 60-70% |
| Glycerine | 5% |
| Caprylic/Capric Triglyceride | 6% |
| Cetearyl Alcohol | 3% |
| Glyceryl Stearate | 3% |
| Dimethicone | 2% |
| Salicylic Acid | 1% |
| Niacinamide | 2% |
| Phenoxyethanol + Ethylhexylglycerin | 1% |
| Xanthan Gum | 0.5% |
| Carbomer | 0.3% |
| Fragrance, Sodium Hydroxide (10% solution) |
Dosing Guidelines
A. Dosing by Application
| Products | Authorized dosage % |
|---|---|
| Ointments/Creams | Upto 0.5% |
| Hair Formulations | 0.5–2% |
About Salicylic Acid
Made through the Kolbe-Schmitt process, where sodium phenoxide reacts with carbon dioxide under heat and pressure. After acidification, the process gives a good yield of about 80–90%.
Made through the Kolbe-Schmitt process, where sodium phenoxide reacts with carbon dioxide under heat and pressure. After acidification, the process gives a good yield of about 80–90%. Raw Material: Phenol(C6H5OH), Sodium Hydroxide(NaOH), CO2, Sulfuric Acid(H2SO4) or HCl Overall Reaction: C6H5ONa + CO2 + HCl --> C7H6O3(Salicylic acid) + NaCl
About Salicylic Acid
Made through the Kolbe-Schmitt process, where sodium phenoxide reacts with carbon dioxide under heat and pressure. After acidification, the process gives a good yield of about 80–90%.
Made through the Kolbe-Schmitt process, where sodium phenoxide reacts with carbon dioxide under heat and pressure. After acidification, the process gives a good yield of about 80–90%. Raw Material: Phenol(C6H5OH), Sodium Hydroxide(NaOH), CO2, Sulfuric Acid(H2SO4) or HCl Overall Reaction: C6H5ONa + CO2 + HCl --> C7H6O3(Salicylic acid) + NaCl
Regulatory Compliance
| Region | Max Allowed Level | Notes | Certification Body |
|---|---|---|---|
| China | - | No statutory maximum | NMPA - National Medical Products Administration |
| India | - | Follows EU standards for cosmetics | - |
| Japan | 0.2% | 0.2% for all cosmetic uses. | MHLW – Ministry of Health, Labour and Welfare |
| Korea, Republic of | - | No statutory maximum | MFDS - Ministry of Food and Drug Safety |
| United States | 2% | The maximum allowed concentration is 2.0% for OTC acne treatment. | FDA |
| ASEAN | - | No statutory maximum | - |
| European Union | - | SCCS consider Salicylic acid safe when used at max conc. Of 3.0% for the cosmetic rinse-off hair products, 0.5% for body lotion, eye shadow, mascara, eyeliner, lipstick, oral products and non-spray deodorant and 2.0% for other products | SCCS (Scientific Committee on Consumer Safety) |
FAQs - Salicylic Acid
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